Why the study?
Prosthetic valve embolization is a serious complication of transcatheter aortic valve replacement, and there are no established pharmaceutical guidelines for the management of patients with valve prosthesis embolization.
This case report demonstrates a potential management strategy for TAVI embolization involving a second valve implantation and combined antithrombotic therapy in the absence of established guidelines.
Emphasizes vigilance for rare TAVR embolism; leaves open evidence-based prevention and treatment strategies.
Transcatheter aortic valve implantation is rapidly emerging as the leading treatment for severe aortic valve stenosis, especially in elderly and high-risk or inoperable patients. Prosthetic embolism is a rare but serious complication of transcatheter aortic valve replacement. Patients who develop prosthetic embolism are at increased risk of mortality and morbidity. These include stroke and aortic dissection associated with manipulation of the prosthesis in the ascending aorta. Treatment of valve embolisms into the aorta may differ depending on the type of valve; however, it traditionally relies on repositioning the valve to an appropriate position. To date, there are no established pharmaceutical guidelines for the management of patients with valve prosthesis embolization. We present a case report of the implantation of a second aortic valve prosthesis after periprocedural embolization of the first transcatheter valve, resulting in residual floating in the ascending aorta and following treatment with oral anticoagulation as well as single antiplatelet therapy due to the increased risk of thrombogenesis. This case report provides an example of the management of a transcatheter valve embolization with residual floating and highlights the need for further studies to address this issue.
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Ratyte et al. (2025) studied this question.
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