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Database surveillance study reveals rising trimethoprim-sulfamethoxazole resistance in methicillin-resistant Staphylococcus aureus, highlighting the need for tailored antibiotic prescribing.
We reviewed trimethoprim-sulfamethoxazole antibiotic susceptibility testing data among Staphylococcus aureus using 3 national inpatient databases. In all 3 databases, we observed an increases in the percentage of methicillin-resistant Staphylococcus aureus that were not susceptible to trimethoprim-sulfamethoxazole. Providers should select antibiotic regimens based on local resistance patterns and should report changes to the public health department.
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Ham et al. (2022) studied this question.
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