Viewpoint: a proposal for a simple algorithm for managing oral anticoagulation and antiplatelet therapy in patients with non-valvular atrial fibrillation and coronary stents
Population
Patients with non-valvular atrial fibrillation requiring oral anticoagulation who undergo percutaneous…
Design
Review
Authors
Discussion
Loading...
Member takes
Implication
Supports shorter antithrombotic regimens in AF-PCI; leaves open optimal strategy for high ischemic-risk subgroups.
Structured PICO
P
Population
Patients with non-valvular atrial fibrillation requiring oral anticoagulation who undergo percutaneous coronary intervention (PCI) with bare-metal or second-generation drug-eluting stents
I
Intervention
A simplified three-stage antithrombotic regimen: Stage I (up to 1 month) aspirin + clopidogrel + non-vitamin K antagonist oral anticoagulant (NOAC); Stage II (1 to 6 months) clopidogrel + NOAC; Stage III (indefinite) NOAC alone
A simplified three-stage antithrombotic regimen is proposed for patients with non-valvular AF undergoing PCI to minimize bleeding risk while preventing stroke and stent thrombosis.
Cite This Study
Steg et al. (2015) studied this question.