Why the study?
Does elevated plasma homocysteine concentration predict early and late cardiac events in patients with acute coronary syndromes?
Population
440 patients admitted with acute coronary syndromes to a single unit.
Comparison
Elevated plasma homocysteine concentration vs Lower plasma homocysteine concentration
Design
Cohort
Follow-up
median 2.5 years
Authors
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Elevated homocysteine may refine post-ACS risk stratification; leaves open whether lowering it reduces events.
Does elevated plasma homocysteine concentration predict early and late cardiac events in patients with acute coronary syndromes?
Elevated total homocysteine levels on admission strongly predict late cardiac events in patients with acute coronary syndromes.
Stubbs et al. (2000) studied this question.
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