Why the study?
Takotsubo cardiomyopathy is associated with physical or emotional stress, but delirium state as a cause is rarely reported.
This report highlights a rare case of delirium acting as a stressor to induce Takotsubo cardiomyopathy, which resolved with supportive care.
Alerts clinicians to possible medication-related Takotsubo in the elderly; leaves open causal links and generalizability.
An 85-year-old woman presented with altered mental status and appeared to be actively agitated due to her medications. During her hospitalization, troponins trended up and an electrocardiogram (ECG) showed diffuse ST elevation. Echocardiogram showed an estimated ejection fraction of 40% with hypokinesis of the apex, suggestive of Takotsubo cardiomyopathy. After several days of supportive care, the patient showed significant clinical improvement with normalization of ECG, cardiac enzymes, and echocardiographic findings. Although Takotsubo cardiomyopathy has been associated with diverse forms of physical or emotional stress, this report discusses a rare case of delirium state causing Takotsubo cardiomyopathy.
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Akinboboye et al. (2023) studied this question.
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