Why the study?
Although rare, cardiac manifestations must be considered in the management of patients presenting with myasthenia gravis crisis.
Cardiac manifestations such as Takotsubo cardiomyopathy must be considered in the management of patients presenting with a myasthenic crisis.
Cardiac arrest may signal occult myasthenic crisis; case reports leave open incidence, mechanisms, and screening needs.
Myasthenia gravis (MG) is an autoimmune disorder of the neuromuscular junction that affects skeletal muscles causing weakness, typically the ocular, facial, oropharyngeal, respiratory, and limb muscles. Patients can present as either an MG exacerbation with weakness of any muscle group or an MG crisis which is a life-threatening weakness of the respiratory muscles that usually requires intubation and mechanical ventilation; however, though rare, cardiac manifestations must be considered in the management of such patients.
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Ramrattan et al. (2022) studied this question.
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