Why the study?
Myocardial involvement in myasthenia gravis is rare but can be life-threatening and easily overlooked due to symptom overlap with myasthenic exacerbation, making early recognition of clinical and immunological features essential.
Population
74-year-old woman with myasthenia gravis complicated by myocarditis
Design
Case report
Follow-up
4-month
Key result
Intensified immunotherapy with intravenous immunoglobulin, tacrolimus, and corticosteroids led to rapid resolution of respiratory distress and normalization of cardiac biomarkers and ejection fraction.
Authors
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May warrant cardiac evaluation in MG respiratory distress; leaves open efficacy of intensified immunotherapy.
Case Report (n=1)
No
This case highlights the importance of considering myocarditis in myasthenia gravis patients presenting with respiratory difficulty, emphasizing the need for prompt ECG monitoring and cardiac enzyme assessment.
Mao et al. (2026) conducted a case report in Myasthenia gravis complicated by myocarditis (n=1). Immunosuppressive therapy (pyridostigmine, IVIG, tacrolimus, corticosteroids) was evaluated on Clinical and cardiac recovery. Intensified immunotherapy with intravenous immunoglobulin, tacrolimus, and corticosteroids led to rapid resolution of respiratory distress and normalization of cardiac biomarkers and ejection fraction.
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