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August 9, 2026PLoS ONEOpen Access

Hemodynamic, neurological, and cognitive outcomes after surgical revascularisation in occlusive cerebrovascular disease: Study protocol for single-arm interventional cohort study

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Authors

CNChingiz Nurimanov KMKarashash MenlibayevaKing's College London IMIroda MammadinovaNational Research Center for Maternal and Child Health

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Implication

Single-arm interventional study assesses neurological, cognitive, and hemodynamic outcomes in occlusive cerebrovascular disease patients, indicating potential improvements in surgical care.

Key Points

The study aims to evaluate the neuro-radiological, clinical, and cognitive outcomes after surgical revascularisation in chronic internal carotid artery occlusion patients.
Single-centre, prospective, open-label interventional longitudinal study
Involves 60 patients undergoing STA-MCA bypass
Primary endpoint: incidence of ischemic stroke during 6-month follow-up
Detailed evaluations pre- and post-surgery including angiographic and perfusion imaging assessments
Assessment of neurological and cognitive functions using standard tests
Aim to correlate postoperative findings with clinical outcomes to enhance decision-making.

Cite This Study

Nurimanov et al. (2026) studied this question.

synapsesocial.com/papers/6a782d182e1896536c83fe6d https://doi.org/10.1371/journal.pone.0354103

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Implication

Single-arm interventional study assesses neurological, cognitive, and hemodynamic outcomes in occlusive cerebrovascular disease patients, indicating potential improvements in surgical care.

Hemodynamic, neurological, and cognitive outcomes after surgical revascularisation in occlusive cerebrovascular disease: Study protocol for single-arm interventional cohort study

Discussion

Member takes

Implication

Key Points

Cite This Study

Hemodynamic, neurological, and cognitive outcomes after surgical revascularisation in occlusive cerebrovascular disease: Study protocol for single-arm interventional cohort study

Discussion

Member takes

Implication

Key Points

Cite This Study

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