Three studies identify CDC42 as a key regulator of pyrin inflammasome activation, suggesting a novel mechanism.
Three studies identify CDC42 as binding partner of the pyrin B30.2 domain, establishing a previously unrecognized mechanism regulating pyrin inflammasome activation (see related Research Articles by Aoki et al. , Feng et al. , and Iwata et al. )
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Fiachra Humphries (2026) studied this question.
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