Why the study?
Does atropine attenuate the increase in plasma GIP during insulin-induced hypoglycemia in humans?
Does atropine attenuate the increase in plasma GIP during insulin-induced hypoglycemia in humans?
The vagal nerves play a major role in the release of plasma GIP during hypoglycemia, as demonstrated by the attenuating effect of atropine.
Answers are grounded in this paper and cite their sources.
Supports vagal role in GIP release during hypoglycemia; leaves open any therapeutic implications.
Insulin-induced hypoglycemia caused a modest but significant (p = 0.031) increase in plasma GIP. This increase was significantly (p = 0.031) attenuated when atropine was given together with insulin, indicating that the vagal nerves play a major role in the release of plasma GIP during hypoglycemia.
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Jorde et al. (1981) studied this question.
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