Key result
A young woman developed subacute spontaneous thrombosis of a percutaneous Melody valve 15 months after placement in the tricuspid position, requiring surgical replacement.
Case Report (n=1)
This case highlights the potential for spontaneous thrombosis of a Melody valve in the tricuspid position, suggesting that anticoagulation strategies may need to be reconsidered in this setting.
Alerts clinicians to possible late thrombosis risk with Melody valve in tricuspid position; leaves open questions on optimal antithrombotic regimens.
The percutaneous Melody valve is occasionally used for the treatment of bioprosthetic valve dysfunction and is an attractive option for patients at high risk for repeat operation. Anticoagulation is not routinely recommended following Melody valve placement. We present the case of a young woman who developed subacute spontaneous thrombosis of her Melody valve 15 months after placement. Her clinical status was compromised by severe tricuspid prosthesis stenosis and right-to-left shunting across a small residual atrial septal defect. Surgical replacement was required. To our knowledge, this is the first reported case of spontaneous thrombosis of a Melody valve in the tricuspid position.
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Reddy et al. (2015) conducted a case report in Prosthetic Tricuspid Stenosis (n=1). Melody valve placement was evaluated on Spontaneous thrombosis. A young woman developed subacute spontaneous thrombosis of a percutaneous Melody valve 15 months after placement in the tricuspid position, requiring surgical replacement.
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