Laboratory study demonstrates stabilization of pre-epithelial mucus gel in rat colon cryostat sections with celloidin, highlighting improved preservation of the protective mucosal layer.
Gastrointestinal mucus occurs partly as a stable, translucent water-insoluble gel adherent to the mucosal surface, and partly in a water soluble form in the lumen (Allen and Carroll 1985). The adherent pre-epithelial mucus gel (PMG) has been shown in unfixed sections of rat stomach as a continuous layer of median thickness 80 μm (Kerss et al. 1982), and 145 μm (Sandzén et al. 1988), respectively.
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Szentkuti et al. (1990) studied this question.
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