Key result
Among older adults at high risk for cardiovascular disease in Eastern China, the overall prevalence of dementia was 12.7% and mild cognitive impairment was 24.3%.
Why the study?
Cardiovascular factors increase dementia risk, but whether a population with high cardiovascular risk has a higher prevalence of cognitive impairment required investigation.
Cross-Sectional (n=3,082)
Yes
Cognitive impairment is highly prevalent among older adults at high cardiovascular risk, highlighting the potential importance of managing cardiovascular risk factors to reduce the dementia burden.
High-CVD-risk adults may warrant cognitive screening consideration; leaves open causal links and preventive effects.
Cardiovascular factors increased the risk of dementia. We investigated the associations between such factors, and tested that if a population with a high level of cardiovascular risk would have a higher prevalence of cognitive impairment. Participants (n=3082; ages=55+; 46.4% female) at high risk of CVD in Zhejiang province Registry for PEACE Million Persons Project, completed 3+ neuropsychological evaluations. Age-, gender- standardized prevalence rates were calculated based on the sixth population census for population of China. Adjusted logistic regression models were used to ascertain the risk factors of dementia. Trial registration number: NCT02536456. There was a high prevalence of cognitive Impairment, coupled with the fact that stroke, diabetes, hypertension and depression were significant risk factors. Cognitive impairment are highly prevalent among elderly at high risk of CVD in Zhejiang province. More population-based strategies, including preventing CVD and reducing cardiovascular risk factors would be an effective way to reduce the dementia burden.
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Li et al. (2020) conducted a cross-sectional in High cardiovascular disease risk (n=3,082). High cardiovascular disease risk was evaluated on Prevalence of dementia (95% CI 11.5-13.8). Among older adults at high risk for cardiovascular disease in Eastern China, the overall prevalence of dementia was 12.7% and mild cognitive impairment was 24.3%.
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