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Enables serial myocardial 31P NMR in closed-chest dogs; leaves open translation to clinical cardiac spectroscopy.
A chronic closed chest dog model was developed to study myocardial metabolism with NMR spectroscopy. Cardiac windows were surgically created in 10 dogs by removal of two ribs and accompanying skeletal muscle. Marlex mesh was sewn between the two exposed ribs, and fascia and skin were closed. 31P spectra were obtained using a surface coil placed into the surgically created pouch and using routine NMR pulsing techniques.
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Osbakken et al. (1986) studied this question.
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