Key result
Waist-to-hip ratio and visceral fat area were significantly positively correlated with brachial-ankle and carotid-femoral pulse wave velocities in renal transplant recipients.
Why the study?
Arterial stiffness and altered body composition are risk factors for cardiovascular-related adverse outcomes after kidney transplantation, but their specific relationship required assessment.
Do obesity and fat tissue parameters correlate with arterial stiffness in renal transplant recipients?
Cross-Sectional (n=344)
Do obesity and fat tissue parameters correlate with arterial stiffness in renal transplant recipients?
Visceral fat and obesity parameters correlate with increased arterial stiffness in renal transplant recipients, highlighting their potential utility as cardiovascular risk markers in this population.
May link arterial stiffness to body composition changes in renal transplant recipients; leaves open cardiovascular outcome prediction.
OBJECTIVE: Arterial stiffness and altered body composition (increased body fat mass [BFM] and decreased lean body mass) are acknowledged risk factors for adverse outcomes after kidney transplantation related to cardiovascular diseases. The aim of the study was the assessment of the relationship between arterial stiffness and fat tissue parameters in renal transplants recipients (RTrs). METHODS: A group of 344 RTrs with stable disease and a mean age of 52.7 years (62.5% men) who underwent transplantation between 1994 and 2018 were randomly enrolled in the study. The following parameters of arterial stiffness were measured: brachial-ankle and carotid-femoral pulse waves velocities (baPWVs left and right, cfPWVs). The obesity and fat tissue (body mass index [BMI], waist-to-hip ratio [WHR], BFM, fat free mass [FFM], percent body fat [PBF], trunk segmental fat analysis [TSFA], and visceral fat area [VFA]) parameters were assessed with InBody 170. We found significant positive correlations among WHR, VFA, baPWV right, baPWV left, and cfPWV. CONCLUSIONS: Obesity and visceral fat tissue influence on arterial stiffness. The analysis of magnitude of obesity and body fat tissue parameters can be used as an additional cardiovascular risk factor in RTrs.
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Heleniak et al. (2020) conducted a cross-sectional in Renal transplant recipients (n=344). Obesity and fat tissue parameters was evaluated on Correlation between arterial stiffness and fat tissue parameters. Waist-to-hip ratio and visceral fat area were significantly positively correlated with brachial-ankle and carotid-femoral pulse wave velocities in renal transplant recipients.
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