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July 12, 2012American Journal of HypertensionOpen Access

Body Mass Index Is Not Independently Associated With Increased Aortic Stiffness in a Brazilian Population

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Key result

Body mass index was not independently associated with increased aortic stiffness after multivariate adjustment (β = -103, P < 0.01).

Population

1,608 individuals aged 25-64 years from Vitória, Brazil

Design

Cross-sectional

Authors

SRSérgio Lamêgo RodriguesUniversidade Federal Rural de PernambucoMBMarcelo Perim BaldoUniversidade Estadual de Montes ClarosLLLorenzo LaniAzienda USL di Bologna

Discussion

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Implication

Questions independent BMI-aortic stiffness link; leaves open blood pressure confounding in prior observations.

Study Design

Type

Cross-Sectional (n=1,608)

Structured PICO

P
Population
1,608 individuals aged 25-64 years from Vitória, Brazil, evaluated for the association between obesity and aortic stiffness.
O
Outcome
Aortic stiffness measured by carotid-femoral pulse wave velocity (PWV)surrogate

Main Result

Effect estimate: β = -103

p-value: p=< 0.01

Obesity is not independently associated with increased aortic stiffness, suggesting that previously reported associations are likely confounded by the progressive increase in blood pressure observed in obesity.

Cite This Study

Rodrigues et al. (2012) conducted a cross-sectional in Aortic stiffness (n=1,608). Body mass index was evaluated on Aortic stiffness (carotid-femoral pulse wave velocity) (β = -103, p=< 0.01). Body mass index was not independently associated with increased aortic stiffness after multivariate adjustment (β = -103, P < 0.01).

synapsesocial.com/papers/6a787cb49d809400dabd7709https://doi.org/10.1038/ajh.2012.91
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