Key result
Diastolic phase TRANCE MRI provided significantly higher contrast-to-noise ratios in the pulmonary veins and left atrium compared to 3D SSFP MRI (e.g., RSPV CNR 56.60 vs 23.60, p<0.05).
Why the study?
The image quality and visibility of TRANCE in diastolic phase compared with 3D SSFP sequences for evaluating the pulmonary vein and left atrium had not been established.
Does TRANCE MRI in the diastolic phase improve image quality of the pulmonary veins and left atrium compared to 3D SSFP in healthy volunteers?
Cross-Sectional (n=10)
No
Does TRANCE MRI in the diastolic phase improve image quality of the pulmonary veins and left atrium compared to 3D SSFP in healthy volunteers?
Absolute Event Rate: 56.6% vs 23.6%
p-value: p=<0.05
Diastolic phase TRANCE MRI provides significantly better contrast-to-noise ratio and visual image quality of the pulmonary veins and left atrium compared to 3D SSFP, offering a promising non-contrast option for pre-ablation planning.
May aid non-contrast PV/LA MRI in select cases; leaves open clinical adoption pending larger validation studies.
OBJECTIVE: The aim of this study was to compare the image quality and the visibility of trigger angiography non-contrast enhanced (TRANCE) in diastolic phase and 3D balanced steady-state free precession (3D SSFP) sequences for the evaluation of pulmonary vein (PV) and left atrium (LA). METHODS: About 10 volunteers underwent TRANCE and 3D SSFP imaging on 1.5 T MRI. Axial images were reconstructed and regions of interest were positioned on the right superior pulmonary vein (RSPV), right inferior pulmonary vein (RIPV), left superior pulmonary vein (LSPV), left inferior pulmonary vein (LIPV), LA, and left atrial appendage (LAA). Contrast-to-noise ratio (CNR) between each part and muscle were calculated and compared between two sequences. The two observers independently scored the image quality of each image on the basis of PV, LA, and LAA anatomy and contour using a five-point scale, which scores were averaged and compared. RESULTS: CNRs on RSPV, RIPV, LSPV, LIPV, LA, and LAA were significantly higher in TRANCE sequence compared with 3D SSFP sequence. On visual assessment, TRANCE showed significantly higher scores in RSPV, RIPV, LSPV, LIPV compared with 3D SSFP sequence. CONCLUSIONS: TRANCE provides higher image quality in PVs and LA compared with 3D SSFP on 1.5 T MRI. On visual assessment, TRANCE provides better visibility of PVs anatomy and contour compared with 3D SSFP.
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Misaka et al. (2019) conducted a cross-sectional in Healthy volunteers (n=10). Trigger angiography non-contrast enhanced (TRANCE) MRI in diastolic phase vs. 3D balanced steady-state free precession (3D SSFP) MRI was evaluated on Contrast-to-noise ratio (CNR) of the right superior pulmonary vein (RSPV) (p=<0.05). Diastolic phase TRANCE MRI provided significantly higher contrast-to-noise ratios in the pulmonary veins and left atrium compared to 3D SSFP MRI (e.g., RSPV CNR 56.60 vs 23.60, p<0.05).
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