Key result
Ambulatory monitoring across daily environments revealed that heart rate variability decreased during sleep (P<0.001), whereas blood pressure variability increased (P<0.001).
Why the study?
How do blood pressure and heart rate variability change across different daily environments (work, home, sleep) in healthy premenopausal women?
Observational (n=206)
How do blood pressure and heart rate variability change across different daily environments (work, home, sleep) in healthy premenopausal women?
p-value: p=<0.001
In healthy premenopausal women, heart rate variability follows expected patterns with behavior and activity across daily environments, whereas blood pressure variability paradoxically increases during sleep.
Nocturnal BPV rise despite HRV drop warrants no practice change; leaves open prognostic value in premenopausal women.
OBJECTIVES: As daily environments change, behavior and activity also change and as blood pressure (BP) and heart rate (HR) are allostatically tied to these factors, one might expect that environments that elicit the greatest behavioral/activity variation should also evince the highest BP and HR variability [standard deviation (SD) or coefficient of variation (CV)]. The purpose of this study was to evaluate this premise. METHODS: Two hundred and six women (age = 37.6 ± 9.1 years) wore an ambulatory BP monitor on a midweek workday. All worked in clerical, technical, or professional positions. Ambulatory BP and HR Means, SDs and CVs at work (11 AM-3 PM), home (∼6-10 PM) and during sleep (∼10 PM-6 AM) were compared using repeated measures ANCOVA. RESULTS: Mean BP and HR decreased from work and home to sleep [121 ± 11, 120 ± 11 vs. 107 ± 12 systolic; 82 ± 10, 80 ± 11 vs. 66 ± 11 diastolic; 79 ± 12, 80 ± 12 vs. 68 ± 11 HR (all P < 0.001)], while the CV of systolic and diastolic BP increased [0.06 ± 0.02, 0.07 ± 0.02 vs. 0.08 ± 0.03 systolic; 0.09 ± 0.03, 0.10 ± 0.04 vs. 0.12 ± 0.05 diastolic (P < 0.001)]. The HR SD decreased during sleep [8.1 ± 3.8, 8.2 ± 3.8 vs. 6.9 ± 3.2 (P < 0.001)]. CONCLUSIONS: HR variability follows the expected variability pattern with behavior and activity, whereas BP does not.
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James et al. (2014) conducted an observational in Healthy premenopausal women (n=206). Daily environments (work, home, sleep) vs. Within-subject comparison across environments was evaluated on Blood pressure and heart rate variability (standard deviation or coefficient of variation) (p=<0.001). Ambulatory monitoring across daily environments revealed that heart rate variability decreased during sleep (P<0.001), whereas blood pressure variability increased (P<0.001).
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