Sweet utility: An efficient approach, using a key cyclic sulfate intermediate is reported for the synthesis of mannose-6-phosphate (M6P) analogues modified at the C-6 position. These analogues represent the first known monosaccharide effectors of angiogenesis; furthermore, the results reported here confirm the involvement of the M6P receptor in blood vessel formation.
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Barragan‐Montero et al. (2011) studied this question.
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