Self-reported physical activity and major adverse events in patients with atrial fibrillation: a report from the EURObservational Research Programme Pilot Survey on Atrial Fibrillation (EORP-AF) General Registry
Key result
Self-reported regular and intense physical activity in patients with atrial fibrillation was associated with lower rates of cardiovascular death, all-cause death, and composite outcomes (P < 0.0001).
Why the study?
Does self-reported physical activity reduce major adverse events in patients with atrial fibrillation?
Population
2,442 patients with atrial fibrillation enrolled in the EURObservational Research Programme on AF Pilot Survey
Comparison
Self-reported physical activity vs No physical activity ('none')
Design
Cohort
Follow-up
1-year
Authors
Discussion
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Member takes
Implication
Should not yet change AF practice; hypothesis-generating and requires randomized confirmation.
Study Design
Type
Observational (n=2,442)
Multicenter
Yes
Structured PICO
Does self-reported physical activity reduce major adverse events in patients with atrial fibrillation?
P
Population
2,442 patients with atrial fibrillation from the EORP-AF Pilot Survey, followed for 1 year to assess the association between self-reported physical activity and major adverse events.
E
Exposure
Self-reported physical activity (categorized as occasional, regular, or intense)
C
Comparator
No physical activity ('none')
O
Outcome
Cardiovascular death, all-cause death, and composite outcomes (CV death/any thromboembolic event/bleeding) at 1-year follow-upcomposite
Main Result
p-value: p=< 0.0001
In patients with atrial fibrillation, any level of physical activity is associated with a lower risk of all-cause death and composite cardiovascular outcomes at 1 year.
Cite This Study
Proietti et al. (2016) conducted an observational in Atrial fibrillation (n=2,442). Physical activity vs. No physical activity was evaluated on CV death, all-cause death, and composite outcomes (p=< 0.0001). Self-reported regular and intense physical activity in patients with atrial fibrillation was associated with lower rates of cardiovascular death, all-cause death, and composite outcomes (P < 0.0001).