Key result
Every percentile increase in preoperative state anxiety led to an extra 0.068 mg of morphine being administered to maintain mild pain levels in the 48 hours following cardiac surgery.
Why the study?
Patients undergoing cardiac surgery present pain management challenges, and the influence of preoperative anxiety levels on postoperative pain and analgesic requirements needed evaluation.
Does higher preoperative anxiety increase postoperative analgesic requirements in patients undergoing cardiac surgery?
Population
116 patients undergoing cardiac surgery
Comparison
Levels of preoperative anxiety
Design
Prospective cohort study
Follow-up
48 h post-surgery
Authors
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Preoperative state anxiety was associated with higher morphine requirements after cardiac surgery; supports screening but leaves open whether reduction improves outcomes.
Cohort (n=116)
No
Does higher preoperative anxiety increase postoperative analgesic requirements in patients undergoing cardiac surgery?
Mean Difference: 0.068 (95% CI 0.007–0.129)
p-value: p=0.029
Higher levels of preoperative state anxiety and younger age are significant predictors of greater postoperative analgesia requirements in patients undergoing cardiac surgery.
Fernández‐Castro et al. (2022) conducted a cohort in Cardiac surgery (n=116). Preoperative state anxiety vs. Lower levels of preoperative state anxiety was evaluated on Postoperative analgesic requirements (milligrams of morphine hydrochloride required to maintain pain below 4 on the verbal numerical rating scale) (MD 0.068, 95% CI 0.007-0.129, p=0.029). Every percentile increase in preoperative state anxiety led to an extra 0.068 mg of morphine being administered to maintain mild pain levels in the 48 hours following cardiac surgery.
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