Key result
Ultrasound-guided bilateral transversus thoracic muscle plane block significantly reduced total fentanyl consumption in the first 24 hours postoperatively by a mean difference of 185.143 µg compared to sham block.
Why the study?
The study aimed to evaluate the analgesic efficacy of ultrasound-guided bilateral transversus thoracic muscle plane block after open-heart surgeries.
Does ultrasound-guided bilateral transversus thoracic muscle plane block reduce 24-hour fentanyl consumption and pain in adults undergoing open-heart surgery via median sternotomy?
Population
70 patients aged above 18 years scheduled for valve replacement or adult congenital surgery via median sternotomy
Comparison
Ultrasound-guided bilateral transversus thoracic muscle plane block vs sham block
Design
Randomized controlled study
Authors
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Bilateral TTMP block reduces opioid use and pain after sternotomy; extends RCT evidence supporting regional analgesia in cardiac surgery.
RCT (n=70)
Double-blind
Computer-generated random numbers
No
Does ultrasound-guided bilateral transversus thoracic muscle plane block reduce 24-hour fentanyl consumption and pain in adults undergoing open-heart surgery via median sternotomy?
Mean Difference: -185.143 (95% CI -221.871–-148.415)
Absolute Event Rate: 205.7% vs 390.9%
p-value: p=<0.0001
Bilateral transversus thoracic muscle plane block significantly reduces postoperative opioid consumption and pain scores in patients undergoing open-heart surgery via median sternotomy.
Hamed et al. (2021) conducted an RCT in Postoperative pain after open-heart surgery (n=70). Ultrasound-guided bilateral Transversus Thoracic Muscle Plane Block vs. Sham block (20 mL of 0.9% saline per side) was evaluated on Total fentanyl consumption in the first 24 hours (MD -185.143, 95% CI -221.871 to -148.415, p=<0.0001). Ultrasound-guided bilateral transversus thoracic muscle plane block significantly reduced total fentanyl consumption in the first 24 hours postoperatively by a mean difference of 185.143 µg compared to sham block.
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