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April 29, 2004European Heart Journal

Relative value of N-terminal probrain natriuretic peptide, TIMI risk score, ACC/AHA prognostic classification and other risk markers in patients with non-ST-elevation acute coronary syndromes

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Why the study?

Does NT-proBNP measurement improve prognostic risk stratification for mortality in patients with NSTE-ACS compared to TIMI risk score and ACC/AHA classification alone?

Population

1483 consecutive patients with non-ST-segment-elevation acute coronary syndromes (NSTE-ACS)

Design

Cohort

Follow-up

180 days

Authors

ÓBÓscar Bazzino

Discussion

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Overview

NT-proBNP may refine mortality risk stratification in NSTE-ACS; leaves open prospective validation against TIMI and ACC/AHA scores.

Structured PICO

Does NT-proBNP measurement improve prognostic risk stratification for mortality in patients with NSTE-ACS compared to TIMI risk score and ACC/AHA classification alone?

P
Population
1483 consecutive patients with non-ST-segment-elevation acute coronary syndromes (NSTE-ACS)
I
Intervention
Measurement of NT-proBNP, TnT, myoglobin, and hsCRP at median 3 hours after admission
O
Outcome
In-hospital and 180-day mortalityhard clinical

NT-proBNP is a strong independent predictor of short- and medium-term mortality in NSTE-ACS, adding significant prognostic value beyond standard clinical risk scores.

Cite This Study

Óscar Bazzino (2004) studied this question.

synapsesocial.com/papers/6a78c844c72ca19efaf995c1https://doi.org/10.1016/j.ehj.2004.03.004
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Also Consider

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