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Plasma cell neoplasms encompass a range of disorders, including multiple myeloma (MM) and its precursor condition, monoclonal gammopathy of undetermined significance (MGUS). While prior studies have explored the proteomes of malignant plasma cells, a comprehensive analysis of the proteome of the bone marrow (BM) microenvironment as reflected in BM plasma remains limited [ 1 ].
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Hsu et al. (2025) studied this question.
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