Key result
Preprocedural 3D CT planning yielded LAA ostium diameter measurements closer to the actual device size than TEE (P<0.001) and angiography (P<0.001) in patients undergoing one-stop LAAO and PVi.
Why the study?
The optimal imaging modality for selecting device size in patients with AF undergoing one-stop LAAO with concomitant PVi remains undefined.
Does preprocedural 3D CT planning improve device size selection compared to TEE and angiography in patients with atrial fibrillation undergoing one-stop LAAO and PVi?
Observational (n=22)
Does preprocedural 3D CT planning improve device size selection compared to TEE and angiography in patients with atrial fibrillation undergoing one-stop LAAO and PVi?
p-value: p=<0.001
Preprocedural 3D CT planning is more accurate than intraoperative TEE and angiography for selecting LAAO device size in patients undergoing concomitant PVi.
Preprocedural 3D CT may aid LAA sizing in one-stop procedures; leaves open need for randomized validation before practice change.
Background: The optimal imaging modality for selecting the device size in patients with atrial fibrillation undergoing one-stop left atrial appendage occlusion (LAAO) with concomitant pulmonary vein isolation (PVi) remains undefined. We compared preprocedural 3-dimensional computed tomography (3D CT) with intra-procedural transesophageal echocardiography (TEE) and left atrial appendage (LAA) angiography in guiding one-stage PVi and LAAO. Methods: We measured the LAA ostium diameter using an interactive 3D CT system with a central line-based approach and compared these measurements with those from intra-procedural TEE and angiography, and the actual device size. The optimal compression ratio was used to assess the attainment rates of the three imaging modalities. Results: Twenty-two patients (median age: 68.5 years, 21.8 % female) underwent the one-stage procedure. The median LAA ostium diameter measured by 3D CT (24.3 mm, interquartile range [IQR] = 22.0-27.0 mm) was closer to the Watchman device size (27.0 mm, IQR = 24.0-31.0 mm, P = 0.127) compared to TEE (21.2 mm, IQR = 18.4-22.7 mm, P < 0.001) and angiography (22.5 mm, IQR = 17.9-25.1 mm, P < 0.001). 3D CT had a better attainment rate for the optimal compression ratio than TEE (10.8 %, IQR = 7.4-16.5 % vs. 22.7 %, IQR = 19.2-29.3 %, P < 0.001) and angiography (19.7 %, IQR = 15.1-24.1 %, P = 0.001). All patients underwent successful device implantation without peri-device leak or complications during the periprocedural period and follow-up. Conclusions: In this pilot study, a preprocedural central line-based 3D CT planning system appeared to be more effective than intraoperative TEE and angiography in measuring the LAA ostium diameter to guide device size selection in patients with atrial fibrillation undergoing one-stop LAAO with concomitant PVi.
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Chen et al. (2024) conducted an observational in Atrial fibrillation (n=22). Preprocedural 3-dimensional computed tomography (3D CT) vs. Intra-procedural transesophageal echocardiography (TEE) and left atrial appendage (LAA) angiography was evaluated on LAA ostium diameter measurement and optimal compression ratio attainment (p=<0.001). Preprocedural 3D CT planning yielded LAA ostium diameter measurements closer to the actual device size than TEE (P<0.001) and angiography (P<0.001) in patients undergoing one-stop LAAO and PVi.
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