Pneumocystis Jirovecii Pneumonia: Molecular Diagnosis and Antimicrobial Susceptibility in Two Renal Transplants Cases

Objectives: Pneumocystis jirovecii, a pathogenic fungus, causes severe interstitial pneumonia among immunocompromised patients. The transplant patients are predisposed to P. jirovecii pneumonia (PJP), most notably those under immunosuppressive therapy or with graft rejection. We describe here two cases of renal transplant cases with PJP and demonstrate the importance of molecular biology in the diagnosis and the prevalence of the DHPS gene mutation.