Key result
Perioperative oral management significantly attenuated the decrease in perioperative serum albumin levels in patients undergoing surgery under general anesthesia (adjusted estimate 0.022, p<0.001).
Why the study?
The study investigated the efficacy of perioperative oral managements on perioperative nutritional conditions in patients undergoing surgery with general anesthesia.
Does perioperative oral management improve perioperative serum albumin levels in patients undergoing surgery under general anesthesia?
Observational (n=11,160)
Yes
Does perioperative oral management improve perioperative serum albumin levels in patients undergoing surgery under general anesthesia?
Mean Difference: 0.022
Absolute Event Rate: -0.462% vs -0.468%
p-value: p=<0.001
Perioperative oral management is associated with a significant positive effect on perioperative serum albumin levels in patients undergoing surgery under general anesthesia.
POMs may support perioperative nutrition; leaves open whether prospective trials confirm benefit in surgical patients.
The purpose of the present study was to investigate the efficacy of perioperative oral managements (POMs) on perioperative nutritional conditions in patients undergoing surgery with general anesthesia. Medical records were retrospectively reviewed and the effects of POMs were investigated based on a large number of cases using a multicenter analysis. The profile of serum albumin levels was assessed and compared between patients with and without POMs using the multivariate analysis. Seventeen Eleven thousand and one hundred sixty patients (4,873 males and 6,287 females) were reviewed. Of these, 2710 patients (24.3%) had undergone POMs. The results of a multivariate analysis revealed the significant positive effect of POMs on perioperative serum albumin level (change between at admission and discharge, (Estimate: 0.022, standard error: 0.012, P < .0001). Patient gender, age, surgical site, performance status, the American Society of Anesthesiologists (ASA) physical status classification, operation time, amount of blood loss, and serum albumin level at admission were also significant predictors. Adjusted multivariate analysis of the effects of POMs on perioperative change of serum albumin level in all subjects reveled the significance of POMs intervention (estimate: 0.022, standard error: 0.012, P < .0001). These results suggest that POMs exerts significant positive effects on perioperative serum albumin levels in patients underwent surgery under general anesthesia.
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Yamada et al. (2021) conducted an observational in Patients treated surgically under general anesthesia (n=11,160). Perioperative oral managements (POMs) vs. No perioperative oral management was evaluated on Change in perioperative serum albumin level (between admission and discharge) (Estimate 0.022, p=<0.001). Perioperative oral management significantly attenuated the decrease in perioperative serum albumin levels in patients undergoing surgery under general anesthesia (adjusted estimate 0.022, p<0.001).
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