What question did this study set out to answer?

To determine whether dietary intake of beta carotene, retinol, and specific food groups is associated with a reduced risk of lung cancer among nonsmoking men and women.

January 5, 1994JNCI Journal of the National Cancer Institute

Dietary Beta Carotene and Lung Cancer Risk in U.S. Nonsmokers

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Authors

SMS. T. MayneYale Cancer Center DJDwight T. JanerichFoundation for Blood Research PGPeter GreenwaldCornell University

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Implication

Case-control study finds dietary beta carotene reduces lung cancer risk in nonsmokers, suggesting protective dietary benefits against carcinogenesis.

Key Points

To determine whether dietary intake of beta carotene, retinol, and specific food groups is associated with a reduced risk of lung cancer among nonsmoking men and women.
Population-based, matched case-control study conducted in New York State from 1982 to 1985.
Included 413 individually matched case-control pairs of nonsmoking subjects who completed dietary interviews.
Calculated dietary beta carotene and retinol intakes as weighted sums of monthly consumption frequencies and assessed risk across subgroups.
Dietary beta carotene intake was significantly associated with a reduced risk of lung cancer (OR = 0.70; 95% CI = 0.50–0.99), whereas retinol showed no significant association (OR = 0.98; 95% CI = 0.82–1.17).
Consumption of greens (P for trend < .01), fresh fruits (P for trend < .01), cheese (P for trend < .05), and vitamin E supplements (OR = 0.55; 95% CI = 0.35–0.85) were protective, while whole milk was associated with increased risk (P for trend < .01).
Raw fruit and vegetable consumption showed a significant protective trend in both females (P for trend < .005) and males (P for trend < .005).

Cite This Study

Mayne et al. (1994) studied this question.

synapsesocial.com/papers/6a78fac7e5601668f5020519 https://doi.org/10.1093/jnci/86.1.33

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Implication

Case-control study finds dietary beta carotene reduces lung cancer risk in nonsmokers, suggesting protective dietary benefits against carcinogenesis.

Dietary Beta Carotene and Lung Cancer Risk in U.S. Nonsmokers

Discussion

Member takes

Implication

Key Points

Cite This Study

Dietary Beta Carotene and Lung Cancer Risk in U.S. Nonsmokers

Discussion

Member takes

Implication

Key Points

Cite This Study

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