Key result
Among infants of diabetic mothers, those with congenital heart disease had a statistically significant increase in pulmonary artery systolic pressure compared to healthy controls (p <0.001).
Why the study?
Infants of diabetic mothers are more prone to congenital anomalies, prompting evaluation of the frequency of cardiac complications and the effect of maternal diabetes control.
What is the frequency and pattern of cardiac complications in infants of diabetic mothers in the NICU?
Population
60 neonates of diabetic mothers in the NICU
Comparison
Infants with congenital heart disease vs normal healthy infants
Design
Cross-sectional prospective study
Authors
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Higher cardiac anomaly rates in IDMs support targeted screening; leaves open glycemic control effects pending prospective data.
Cross-Sectional (n=60)
Yes
What is the frequency and pattern of cardiac complications in infants of diabetic mothers in the NICU?
p-value: p=<0.001
Infants of diabetic mothers, particularly those with poor maternal glycemic control, have a high frequency of cardiac complications including PDA, PFO, and hypertrophic cardiomyopathy.
Ali et al. (2021) conducted a cross-sectional in Infants of diabetic mothers (n=60). Congenital heart disease vs. Normal healthy infants of diabetic mothers was evaluated on Pulmonary artery systolic pressure (p=<0.001). Among infants of diabetic mothers, those with congenital heart disease had a statistically significant increase in pulmonary artery systolic pressure compared to healthy controls (p <0.001).
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