September 1, 2000Journal of Applied Physiology
Series-to-parallel transition in the filament lattice of airway smooth muscle
Population
Sheep trachealis muscle
Design
Preclinical
Authors
Discussion
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Member takes
Implication
May explain smooth muscle velocity via lattice shifts rather than cycling rate; leaves open translation to human cardiovascular physiology.
Structured PICO
P
Population
Sheep trachealis muscle
I
Intervention
Tetani stimulation
O
Outcome
Force-velocity curves and velocity slowingsurrogate
Velocity slowing in airway smooth muscle during tetani can be explained by a series-to-parallel change in the filament lattice rather than a change in cross-bridge cycling rate.
Cite This Study
Seow et al. (2000) studied this question.