Key result
Therapeutic hypothermia in a 56-year-old man after cardiac arrest induced prominent Osborn waves and recurrent ventricular fibrillation, which resolved upon rewarming.
Case Report (n=1)
No
Therapeutic hypothermia can induce Osborn waves, which may have arrhythmogenic potential leading to recurrent ventricular fibrillation in some individuals.
Osborn waves during therapeutic hypothermia may trigger ventricular fibrillation; this case leaves open the arrhythmogenic risk across broader populations.
Therapeutic hypothermia (TH) has been used to protect neurological functions in cardiac arrest patient. Although Osborn wave is not pathognomonic of hypothermia, it is a well-known electrocardiogram finding of hypothermic patients. The cellular and ionic mechanisms of the Osborn wave have been suggested, and its relationship to tachyarrhythmias, such as ventricular tachycardia and ventricular fibrillation, is being explored. This case highlights the arrhythmogenic potential of Osborn wave and individual difference in response of TH.
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Kim et al. (2015) conducted a case report in Sudden cardiac arrest (n=1). Therapeutic hypothermia was evaluated on Development of Osborn waves and recurrent ventricular fibrillation. Therapeutic hypothermia in a 56-year-old man after cardiac arrest induced prominent Osborn waves and recurrent ventricular fibrillation, which resolved upon rewarming.
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