Key result
Postoperative acute kidney injury in redo cardiac surgery was associated with increased in-hospital mortality, rising from 5.3% without AKI to 64.1% with AKI stage 3 (p < 0.001).
Why the study?
The incidence, risk factors, and prognostic implications of acute kidney injury in patients undergoing redo cardiac surgery remain poorly defined.
What is the incidence, risk factors, and prognostic impact of acute kidney injury in patients undergoing redo cardiac surgery?
Cohort (n=394)
No
What is the incidence, risk factors, and prognostic impact of acute kidney injury in patients undergoing redo cardiac surgery?
p-value: p=<0.001
Acute kidney injury is a frequent complication after redo cardiac surgery and is strongly associated with increased in-hospital mortality, particularly in severe cases.
AKI after redo surgery signals higher complication risk; observational data leaves open whether prevention strategies improve outcomes.
The incidence, risk factors and prognostic implications of acute kidney injury (AKI) in patients undergoing redo cardiac surgery are still poorly defined. We prospectively collected data on 394 consecutive redo patients between January 2011 and October 2020. Patients were divided into groups according to the occurrence of different degrees of postoperative AKI (No AKI vs. Any AKI; No AKI-AKI 1 vs. AKI 2-3). The relationship between AKI and other major complications was also investigated. Postoperatively, AKI 1 occurred in 124 (31.5%), AKI 2 in 36 (9.1%) and AKI 3 in 64 (16.2%). Higher KDIGO classes were associated with increased in-hospital mortality: 5.3% among patients with no postoperative AKI and 8.9%, 13.9% and 64.1% in patients with AKI 1, 2 and 3, respectively (p < 0.001). Age, baseline hemoglobin, comorbidity, EuroSCORE II, operative time and transfusion during CPB proved to be significantly associated to the occurrence of AKI. Our study confirms the burden and prognostic role of AKI in a large, all comers, single center database of redo cardiac procedures.
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Santo et al. (2024) conducted a cohort in redo cardiac surgery (n=394). Acute kidney injury (AKI) vs. No acute kidney injury was evaluated on in-hospital mortality (p=<0.001). Postoperative acute kidney injury in redo cardiac surgery was associated with increased in-hospital mortality, rising from 5.3% without AKI to 64.1% with AKI stage 3 (p < 0.001).
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