Key result
Severe obstructive sleep apnea syndrome is associated with a significant reduction in visual evoked potential p100 wave amplitudes compared to healthy subjects, indicating early optic nerve dysfunction.
Observational (n=30)
No
Absolute Event Rate: 9.4% vs 11.34%
p-value: p=0.042
Reduced VEP amplitudes indicate early optic nerve dysfunction in severe OSAS; hypothesis-generating for screening before larger prospective confirmation.
To evaluate retinal nerve fiber layer thickness (RNLF) with optical coherence tomography (OCT) and optic nerve function with visual evoked potential (VEP) in patients with obstructive sleep apnea syndrome (OSAS).
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Mualla et al. (2018) conducted an observational in Obstructive Sleep Apnea Syndrome (n=30). Obstructive Sleep Apnea Syndrome vs. Healthy subjects was evaluated on VEP-120' p100 wave amplitude (μv) (p=0.042). Severe obstructive sleep apnea syndrome is associated with a significant reduction in visual evoked potential p100 wave amplitudes compared to healthy subjects, indicating early optic nerve dysfunction.
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