Key result
End-to-side implantation of the vascular bioprosthesis resulted in a 13% lower maximum flow velocity (0.95 m/s vs 1.1 m/s) and a 12% larger vortex zone compared to end-to-end implantation.
Why the study?
Assessing blood flow in xenogenic vascular bioprostheses is complicated by variable inner surface geometry that can induce vortex zones and abnormally high velocities, particularly when used as a shunt.
Computational modeling reveals that the implantation geometry of vascular bioprostheses significantly alters hemodynamics, highlighting the importance of connection methods in preventing abnormal flow velocities and vortex formation.
Geometry may inform bioprosthesis design; leaves open effects on clinical outcomes.
The study of blood flow in vascular bioprostheses is a rather complicated task, since the shape of the inner surface of the bioprosthesis is variable, due to xenogenic origin. Because of this, vortex zones can occur inside the vascular bioprosthesis. In addition, the flow structure may contain sections where the flow velocity is abnormally high. It is all the more difficult to assess the nature of the course when using this vascular bioprosthesis as a shunt. A numerical comparison of the blood flow in a bioprosthesis connected to the main vascular bed using the «end-to-end» and «end-to-side» methods (bypass) taking into account the heart rate and blood pressure was performed. It is shown that, due to the nonlinearity of the initial bioprosthesis geometry, the implantation method affects the blood flow. Because of this, vortex zones arise and, with certain combinations of parameters, the effects of «separation» of vortices.
No takes yet. Share an insight, caveat, or question.
Onishchenko et al. (2021) studied Peripheral artery disease. End-to-side implantation (bypass) vs. End-to-end implantation was evaluated on Maximum flow velocity (m/s). End-to-side implantation of the vascular bioprosthesis resulted in a 13% lower maximum flow velocity (0.95 m/s vs 1.1 m/s) and a 12% larger vortex zone compared to end-to-end implantation.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: