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This study aims to understand why mechanical thrombectomy fails in treating acute ischemic stroke.

January 23, 2020Neurological SciencesOpen Access

Why we fail: mechanisms and co-factors of unsuccessful thrombectomy in acute ischemic stroke

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This study aims to understand why mechanical thrombectomy fails in treating acute ischemic stroke.
Analyzed 596 patients with acute ischemic stroke undergoing mechanical thrombectomy.
Failure defined as mTICI score of 0, 1, or 2a and compared with successful cases.
Evaluated demographics, medical history, stroke presentation, and treatment of patients.
16.8% of interventions (100 out of 596) failed, with thrombus access issues in 20 cases.
Thrombus could be passed with the device in 80% of failures, but recanalization did not occur.
Coagulation disorders were linked to poor outcomes, while atrial fibrillation was tied to successful recanalization.

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Randomized trial analyzes reasons for failed thrombectomy interventions in acute ischemic stroke, suggesting device improvements.

Heider et al. (2020) studied this question.

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