Key result
Mechanical thrombectomy was successfully utilized in all 11 published cases of TAVI-related periprocedural stroke, resulting in a significant reduction in NIHSS score and no complications.
Why the study?
Stroke remains a significant complication of TAVI with high mortality and morbidity, prompting a review of the role of mechanical thrombectomy in managing TAVI-related periprocedural stroke.
Does mechanical thrombectomy successfully treat TAVI-related periprocedural stroke?
Systematic Review (n=11)
Does mechanical thrombectomy successfully treat TAVI-related periprocedural stroke?
Mechanical thrombectomy may be a beneficial treatment strategy for TAVI-related periprocedural stroke, avoiding thrombolysis in patients with high bleeding risk and nonthrombotic emboli.
May support dedicated thrombectomy pathways for TAVI stroke; leaves open need for prospective validation.
Transcatheter aortic valve implantation (TAVI) has dramatically altered the treatment of high-risk patients with symptomatic, severe aortic stenosis. Its utilisation has also begun to extend into intermediate- and low-surgical risk patients. Despite major advancements in the field of TAVI, stroke remains a significant complication because of its high mortality and morbidity rate . This article reviews the role of mechanical thrombectomy (MT) in the management of TAVI-related periprocedural stroke. A comprehensive literature search was performed for studies to include in this systematic review of MT in periprocedural and post-TAVI stroke patients. The search identified 11 case reports in which MT was utilised to treat periprocedural stroke successfully. MT without thrombolysis has several potential benefits for TAVI-related periprocedural stroke because a large proportion of strokes are secondary to nonthrombotic emboli and there is a high bleeding risk associated with patients undergoing TAVI. The authors propose that centres undertaking TAVI procedures have dedicated thrombolysis and thrombectomy pathways for patients who experience a TAVI-related periprocedural stroke.
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A 2020 study conducted a systematic review in TAVI-related periprocedural stroke (n=11). Mechanical thrombectomy was evaluated on Reduction in National Institutes of Health Stroke Scale (NIHSS) score. Mechanical thrombectomy was successfully utilized in all 11 published cases of TAVI-related periprocedural stroke, resulting in a significant reduction in NIHSS score and no complications.
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