An Effective WBC Segmentation and Classification Using MobilenetV3–ShufflenetV2 Based Deep Learning Framework

White Blood Cells are essential in keeping track of a person’s health. However, the pathologist’s experience will determine how the blood smear is evaluated. Furthermore, it is still challenging to classify WBCs accurately because they have various forms, sizes, and colors due to distinct cell subtypes and labeling methods. As a result, a powerful deep learning system for WBC categorization based on MobilenetV3-ShufflenetV2 is described in this research. Initially, the WBC images are segmented using an efficient Pyramid Scene Parsing Network (PSPNet). Following that, MobilenetV3 and an Artificial Gravitational Cuckoo Search (AGCS)-based technique are used to extract and select the global and local features from the segmented images. Finally, the WBC images are divided into five classes using a ShufflenetV2 model. The proposed approach is evaluated on blood cell count and detection (BCCD) and Raabin-Wbc datasets and achieves 99.19% and 99% accuracy, respectively. Moreover, the results are satisfactory when compared to existing algorithms.