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Reveals the therapeutic potential of gut microbiota in alleviating acute liver injury from acetaminophen exposure.
In this study, we found that a monoclonal anti-Toll-like receptor 4 antibody can alleviate APAP-induced acute liver injury through changes in the gut microbiota, metabolic pathways, and gut barrier function. This work suggested that the gut microbiota can be a therapeutic target of APAP-induced acute liver injury, and we performed foundation for further research.
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Sun et al. (2023) studied this question.
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