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Comparison
Exogenous pressure perturbations with vs without arterial baroreflex control
Design
White noise analysis
Highlights neural modulation of renal pressure responses in models; leaves open translation to human hypertension management.
We quantified short-term dynamic characteristics of the urine flow (UF) response to arterial pressure (AP) changes using white noise analysis. The UF step response approximated the sum of two exponential decay functions with time constants of ∼6.5 s and 102 s. The neurally mediated antidiuretic (NMA) effect contributed to the slow component of the UF step response, with the magnitude of approximately one-third of that of the pressure diuresis (PD) effect.
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Kawada et al. (2024) studied this question.
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