Recurrent primary intracranial synovial sarcoma, a case report and review of the literature

Figures

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  FIGURE 1. Brain computed tomography (CT) scan revealed an intra axial mass lesion with the central necrotic component and surrounding vasogenic edema in the right frontal white matter causing midline shift to the left side

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  FIGURE 2. Magnetic resonance imaging (MRI) without gadolinium contrast. A:T2 Flair Axial sequence. B:T2 Axial sequence. The above images show an intra axial well‐circumscribed heterogenous mass with central necrosis and surrounding vasogenic edema in right frontal white matter. Magnetic resonance imaging (MRI) with gadolinium contrast C:T1 Axial sequence without gadolinium contrast.D:T1 with gadolinium contrast.E:DWI sequence. The above images show an Intra axial well‐circumscribed heterogenous mass with central necrosis and irregular peripheral enhancement and significant surrounding vasogenic edema in right frontal white matter. restriction of the peripheral solid component of mass was also seen

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  FIGURE 3. The histopathological assessment of the mass shows neoplastic tissue composed of biphasic pattern, large irregular sheets of monotonous cells, some with central necrosis set in fibroblastic stroma. Tumoral cells are plump and have very high N/C ratio. Frequent mitotic figures are present

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  FIGURE 4. IHC staining shows positive reactivity for TLE1, FLI1, and INI1 and negative reactivity for Synaptophysin, Olig 2, SMA, CK and CD 99. The above findings are consistent with SS.

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  FIGURE 5. Brain CT scan showed recurrence of the previous tumor