Radiation Therapy Across Pediatric Hodgkin Lymphoma Research Group Protocols: A Report From the Staging, Evaluation, and Response Criteria Harmonization (SEARCH) for Childhood, Adolescent, and Young Adult Hodgkin Lymphoma (CAYAHL) Group

Radiation therapy (RT) has played a central role in the management of Hodgkin lymphoma (HL) for more than 50 years. Palliative RT was replaced with large fields delivered with curative treatment intent during the 1950s and 1960s.1 Over time, combined modality therapy (CMT) with chemotherapy followed by consolidative RT has increased cure rates while often using less intensive chemotherapy regimens and smaller RT fields at lower doses. The 10-year overall survival now exceeds 85% with CMT for pediatric patients with HL.