Population
Natural IFN-producing cells (NIPC) / plasmacytoid dendritic cells
Comparison
Foot-and-mouth disease virus complexed with… vs Uncomplexed FMDV
Design
Preclinical
Authors
Loading...
May require immune complexes for FMDV to induce pDC IFN-alpha; leaves open in vivo relevance and vaccine implications.
Immune complexes are required for the non-enveloped foot-and-mouth disease virus to induce IFN-alpha responses by plasmacytoid dendritic cells.
Guzylack‐Piriou et al. (2006) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: