Why the study?
Does propofol-induced burst suppression improve neurologic outcome in patients undergoing open cardiac surgery?
Population
225 patients undergoing open cardiac surgery (valve replacement)
Comparison
Induction of electroencephalographic burst… vs Opioid-based anesthetic
Design
Editorial, prospective randomized, trained personnel blinded to group assignment
Follow-up
2 months
Authors
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Pharmacologically induced burst suppression with propofol during cardiac surgery does not improve neurologic outcomes and may increase perioperative morbidity.
Does propofol-induced burst suppression improve neurologic outcome in patients undergoing open cardiac surgery?
Pharmacologically induced burst suppression with propofol during cardiac surgery does not improve neurologic outcomes and may increase perioperative morbidity.
Hindman et al. (1999) studied this question.
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