March 10, 2025Frontiers in NeurologyOpen Access

Profiling chronic migraine patients according to clinical characteristics: a cluster analysis approach

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Why the study?

To group the characteristics of chronic migraine by headache characteristics.

Population

821 adult CM patients visiting a specialized headache outpatient clinic

Comparison

DBSCAN clustering based on headache characteristics

Design

Retrospective medical record analysis

Authors

MKMasahito KatsukiNagaoka University YMYasuhiko MatsumoriMiyagi University of Education SKShin KawamuraOsaka International University

Discussion

Member takes

Implication

Identifies CM subgroups with varying burdens; leaves open whether clusters guide therapy or predict outcomes in prospective studies.

Structured PICO

Population

821 adult chronic migraine (CM) patients who visited a specialized outpatient clinic for headaches

Outcome

Identification of patient clusters and evaluation of burdens to lives, monthly headache days (MHD), monthly acute medication intake days (AMD), and treatment outcomes

Cluster analysis of chronic migraine patients identifies three distinct phenotypes with differing impacts on quality of life but similar treatment outcomes.

Cite This Study

Katsuki et al. (2025) studied this question.

synapsesocial.com/papers/6a79731d14b028facf0dc75b https://doi.org/10.3389/fneur.2025.1569333

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