Why the study?
Does the day of hospital admission affect dexamethasone suppression test (DST) results in patients with primary major depressive disorder?
Population
81 psychiatric inpatients (41 with primary major depressive disorder, 40 with other psychiatric disorders)
Comparison
Dexamethasone suppression test administered on… vs Dexamethasone suppression test administered on…
Design
Cohort
Follow-up
2-6 days
Authors
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DST timing after admission may influence results in primary depression; hypothesis-generating for optimal testing window and needs prospective confirmation.
Does the day of hospital admission affect dexamethasone suppression test (DST) results in patients with primary major depressive disorder?
The timing of the dexamethasone suppression test relative to hospital admission significantly affects cortisol suppression results in patients with primary depression, likely due to admission-related stress.
Coccaro et al. (1984) studied this question.
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