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August 10, 2026Tropical Diseases Travel Medicine and VaccinesOpen Access

A comprehensive look at Respiratory Syncytial Virus (RSV): from pathogenesis to prevention

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Authors

OAOmid Salahi ArdekaniTehran University of Medical SciencesPHParisa HasannezhadGoethe University FrankfurtYGYasaman GoudarziTehran University of Medical Sciences

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Implication

Narrative review examines RSV's epidemiology, clinical manifestations, vaccine development, and therapeutic strategies, highlighting its public health implications.

Key Points

  • This review explores the multifaceted aspects of Respiratory Syncytial Virus (RSV), focusing on its pathogenesis, epidemiology, and prevention strategies.
  • Narrative review of existing literature on RSV's clinical severity and seasonal trends.
  • Analysis of RSV vaccine development, including FDA-approved options and monoclonal antibodies.
  • Discussion of therapeutic strategies and RSV's potential as an oncolytic agent.
  • RSV causes varying degrees of respiratory illness, notably impacting infants and children around the world.
  • Three RSV vaccines—Arexvy, Abrysvo, and mRESVIA—have been approved by the FDA for prevention.
  • Monoclonal antibodies like Nirsevimab and Clesrovimab are recommended for infants to prevent severe RSV disease.

Cite This Study

Ardekani et al. (2026) studied this question.

synapsesocial.com/papers/6a797d299c20a9bbd31844c9https://doi.org/10.1186/s40794-026-00313-3
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