What question did this study set out to answer?

This survey aims to evaluate the management practices for Infantile Epileptic Spasms Syndrome (IESS) in US pediatric hospitals.

August 10, 2026Epilepsia OpenOpen Access

Management of Infantile Epileptic Spasms Syndrome: A survey of US pediatric hospitals

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Authors

AKAkshat KatyayanChildren's Hospital of Wisconsin CAChristina Briscoe AbathBoston University SBSonam BhallaEmory University

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Implication

Survey evaluates management practices of infantile epileptic spasms syndrome in pediatric hospitals, highlighting variability that suggests a need for updated guidelines.

Key Points

This survey aims to evaluate the management practices for Infantile Epileptic Spasms Syndrome (IESS) in US pediatric hospitals.
A 21-question survey was distributed to 45 institutions in the Pediatric Epilepsy Research Consortium.
Responses from 33 institutions were analyzed to identify management practices for IESS.
91% of institutions manage new-onset IESS in-patient; 76% utilize overnight video EEG for diagnosis.
Over 90% conduct MRI and genetic testing at initial diagnosis; common tests include an epilepsy panel (47%) and trio whole exome sequencing (44%).
65% of institutions prefer high-dose prednisolone as first treatment, with most considering surgery only after failure of hormonal therapy and vigabatrin.

Cite This Study

Katyayan et al. (2026) studied this question.

synapsesocial.com/papers/6a797d299c20a9bbd31844da https://doi.org/10.1002/epi4.70309

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Implication

Survey evaluates management practices of infantile epileptic spasms syndrome in pediatric hospitals, highlighting variability that suggests a need for updated guidelines.

Management of Infantile Epileptic Spasms Syndrome: A survey of US pediatric hospitals

Discussion

Member takes

Implication

Key Points

Cite This Study

Management of Infantile Epileptic Spasms Syndrome: A survey of US pediatric hospitals

Discussion

Member takes

Implication

Key Points

Cite This Study

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