July 16, 2015Scandinavian Journal of Trauma Resuscitation and Emergency MedicineOpen Access

Lactate level, etiology, and mortality of adult patients in an emergency department: a cohort study

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Why the study?

Does elevated lactate level predict 7-day mortality across different etiologies in adult emergency department patients?

Structured PICO

Does elevated lactate level predict 7-day mortality across different etiologies in adult emergency department patients?

Population

5,360 adult patients who had lactate measured within 4 hours after arrival to the emergency department at Odense University Hospital, median age 67, 51.7% male.

Intervention

High (≥4 mmol/L) or intermediate (2-3.9 mmol/L) lactate levels

Comparator

Low lactate (0-1.9 mmol/L)

Outcome

7-day mortalityhard clinical

Elevated lactate levels in the emergency department are associated with increased 7-day mortality across most etiologies, except for neurologic and nephrologic/hepatologic conditions.

Discussion

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Implication

Lactate may aid mortality risk stratification across ED etiologies; extends prior observations but leaves open prospective validation before practice change.

Cite This Study

Pedersen et al. (2015) studied this question.

synapsesocial.com/papers/6a798099bdf697b3de0244e9 https://doi.org/10.1186/1757-7241-23-s1-a33

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Implication

Lactate may aid mortality risk stratification across ED etiologies; extends prior observations but leaves open prospective validation before practice change.

Lactate level, etiology, and mortality of adult patients in an emergency department: a cohort study

Structured PICO

Discussion

Implication

Cite This Study

Lactate level, etiology, and mortality of adult patients in an emergency department: a cohort study

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider