What question did this study set out to answer?

To isolate and biochemically characterize a novel equol-producing bacterial strain obtained from human fecal samples.

October 23, 2008Bioscience Biotechnology and BiochemistryOpen Access

Isolation and Characterization of a Novel Equol-Producing Bacterium from Human Feces

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Authors

SYShin‐ichiro YokoyamaGifu Prefectural Research Institute for Forests TSTohru SuzukiGifu University

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Implication

Laboratory isolation study demonstrates daidzein conversion to S-equol by a novel Eggerthella bacterium from healthy human feces, indicating potential applications in gut isoflavone metabolism.

Key Points

To isolate and biochemically characterize a novel equol-producing bacterial strain obtained from human fecal samples.
Isolated bacterial strains from the feces of healthy humans under obligate anaerobic conditions.
Characterized morphology, biochemical properties, 16S rDNA nucleotide sequence homology, and antimicrobial susceptibility.
Tested metabolic conversion capabilities using various isoflavone substrates, including daidzein, dihydrodaidzein, daidzin, glysitein, genistein, and formononetin.
Identified the isolate as a novel pleomorphic, gram-positive bacilliform bacterium designated Eggerthella sp. YY7918, showing 93.3% 16S rDNA sequence homology to Eggerthella hongkongensis HKU10.
Demonstrated that strain YY7918 converts daidzein and dihydrodaidzein into S-equol, but does not metabolize daidzin, glysitein, genistein, or formononetin.
Observed catalase-positive activity, glycerin utilization, gelatin degradation, and susceptibility to aminoglycoside, tetracycline, and new quinolone antibiotics.

Cite This Study

Yokoyama et al. (2008) studied this question.

synapsesocial.com/papers/6a798519fbd9051d3b0dcdd4 https://doi.org/10.1271/bbb.80329

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Implication

Laboratory isolation study demonstrates daidzein conversion to S-equol by a novel Eggerthella bacterium from healthy human feces, indicating potential applications in gut isoflavone metabolism.

Isolation and Characterization of a Novel Equol-Producing Bacterium from Human Feces

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Key Points

Cite This Study

Isolation and Characterization of a Novel Equol-Producing Bacterium from Human Feces

Discussion

Member takes

Implication

Key Points

Cite This Study

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