Why the study?
LV ejection fraction may not truly represent LV systolic function in certain cardiac diseases or may represent more advanced irreversible stages, whereas myocardial strain allows earlier identification of subtle dysfunction.
Does myocardial strain imaging improve the early identification of subtle LV systolic dysfunction compared to LVEF in cardio-oncology patients?
Does myocardial strain imaging improve the early identification of subtle LV systolic dysfunction compared to LVEF in cardio-oncology patients?
Myocardial strain imaging, specifically global longitudinal strain, offers a robust method for early detection of subtle LV systolic dysfunction in cardio-oncology before LVEF declines.
Myocardial strain may detect subclinical LV dysfunction missed by EF; leaves open its routine adoption pending prospective validation.
There is an increasing prevalence of cardiovascular disease and heart failure. Indices of left ventricular (LV) systolic function such as LV ejection fraction used to identify those at risk of adverse cardiac events such as heart failure may not be truly representative of LV systolic function in certain cardiac diseases. Given that LV ejection fraction reduction may represent more advanced irreversible stages of disease, measures of myocardial strain have emerged as a feasible and robust instrument for the early identification of heart disease and subtle LV systolic dysfunction. The purpose of this review was to provide an overview of myocardial strain concepts and emerging clinical applications of global longitudinal strain in cardio-oncology.
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Anastasius et al. (2023) studied this question.
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